de Lange, Cornelia


de Lange,

Cornelia, Dutch pediatrician, 1871-1950. Cornelia de Lange syndrome - Synonym(s): de Lange syndromede Lange syndrome - a congenital anomaly characterized by impaired development, mental retardation, characteristic facies with synophrys and hairline well down on forehead, depressed bridge of nose with uptilted tip of nose, small head with low-set ears, and flat spadelike hands with simian crease and short tapering fingers. Synonym(s): Amsterdam syndrome; Cornelia de Lange syndrome