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chaloneenUK
cha·lone C0230300 (kā′lōn′, kăl′ōn′)n. Any of several polypeptides that cause the reversible inhibition of mitosis in the cells that secrete them.
[From Greek khalōn, present participle of khalān, to slacken.]chalone (ˈkæləʊn) n (Physiology) any internal secretion that inhibits a physiological process or function[C20: from Greek khalōn, from khalan to slacken]chal•one (ˈkæl oʊn)
n. an endocrine secretion that depresses or inhibits physiological activity. [1910–15; < Greek chalôn, present participle of chalân to slacken, loosen; on the model of hormone] chaloneenUK
chalone [kal´ōn] a group of tissue-specific, water-soluble substances that are produced within a tissue and that inhibit mitosis of the cells of that tissue and whose action is reversible.cha·lone (kā'lōn), Originally, a hormone (for example, enterogastrone) that inhibits rather than stimulates; now, mitotic inhibitor (often glycoproteins) elaborated by a tissue and active only on that type of tissue, regardless of species; thus, a reversible tissue-specific mitotic inhibitor. [G. + chalaō, to relax, + -one] chalone (kā′lōn′, kăl′ōn′)n. Any of several polypeptides that cause the reversible inhibition of mitosis in the cells that secrete them.cha·lone (kal'ōn) Any of a number of mitotic inhibitors elaborated by a tissue and active only on that type of tissue, regardless of species; a reversible tissue-specific mitotic inhibitor. [G. + chalaō, to relax, + -one]chalone one of a group of chemicals (PEPTIDES and GLYCOPROTEINS) occurring in living animal tissues which specifically inhibit MITOSIS. |