单词 | ca-125 |
释义 | CA-125CA-125MUC16A gene on chromosome 19p13.2 which encodes a protein that provides a protective lubricating barrier against particles and infectious agents at mucosal surfaces. It is more commonly known as CA125, and is a highly characteristic marker of ovarian carcinomas.CA-125A cell surface glycoprotein expressed on the cell membrane of normal ovarian tissue, ovarian, cervical, endometrium, GI tract, and breast CAs; rising levels indicate a poor prognosis, but low levels are of little clinical utility; CA-125 may also be ↑ in liver disease, acute pancreatitis, renal failure, occasionally in normal ♀, lymphoma |
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