cold urticaria-angioedema

cold urticaria-angioedema

Cold-induced urticaria-angioedema Autonomic nervous system reactivity to low temperatures Clinical forms, acquired After cold exposure, the Pt suffers a pruritic urticarial eruption, potentially evolving into angioedema, accompanied by headaches and wheezing; if the whole body is cooled–swimming in winter, hypotension, collapse, possibly death Hereditary, immediate-type Erythematous maculopapules accompanied by a burning sensation, pyrexia, arthralgias, ↑ WBCs Hereditary, delayed-type Erythematous swelling 9-18 hrs after a cold 'challenge'