| 释义 |
DictionarySeeautoimmune diseasecollagen disease
collagen disease: see autoimmune diseaseautoimmune disease,
any of a number of abnormal conditions caused when the body produces antibodies to its own substances. In rheumatoid arthritis, a group of antibody molecules called collectively RF, or rheumatoid factor, is complexed to the individual's own gamma globulin
..... Click the link for more information. ; collagencollagen
, any of a group of proteins found in skin, ligaments, tendons, bone and cartilage, and other connective tissue. Cells called fibroblasts form the various fibers in connective tissue in the body.
..... Click the link for more information. .collagen disease[′kä·lə·jən di‚zēz] (medicine) Any of various clinical syndromes characterized by widespread alterations of connective tissue, including inflammation and fibrinoid degeneration. collagen disease
col·la·gen dis·ease , collagen-vascular diseasea group of generalized diseases affecting connective tissue and frequently characterized by fibrinoid necrosis or vasculitis; in some collagen diseases, auto-immunization, particularly antinuclear antibodies, has been shown and circulating immune complexes are found. The term is not entirely acceptable because there is no evidence that collagen is primarily involved; "collagen" was once synonymous with "connective tissue" rather than describing a specific fibrinous protein in that tissue.
See also: connective-tissue disease. col·la·gen dis·ease , collagen-vascular disease (kol'ă-jen di-zēz', kol'ă-jen-vas'kyū-lăr) A group of generalized diseases affecting connective tissue and frequently characterized by fibrinoid necrosis or vasculitis; in some collagen diseases, autoimmunization, particularly antinuclear antibodies, has been shown and circulating immune complexes are found. The term is not entirely acceptable because there is no evidence that collagen is primarily involved; "collagen" was once synonymous with "connective tissue" rather than describing a specific protein in that tissue.
See also: connective-tissue diseasecollagen disease A term formerly, and erroneously, applied to such conditions as rheumatic fever, ankylosing spondylitis, polyarteritis nodosa, lupus erythematosus, rheumatoid arthritis and dermatomyositis but now applied to those known to be caused by defects in the chemical structure of collagen and its distribution and quantity. The collagen diseases include solar and senile elastosis, SCURVY, STRIAE, KELOIDS, PEYRONIE'S DISEASE, PSEUDOXANTHOMA ELASTICUM and the EHLERS-DANLOS SYNDROME.col·la·gen dis·ease , collagen-vascular disease (kol'ă-jen di-zēz', kol'ă-jen-vas'kyū-lăr) Generalized disorder affecting connective tissue. |