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agonist
ag·o·nist A0146300 (ăg′ə-nĭst)n.1. Physiology A contracting muscle that is resisted or counteracted by another muscle, the antagonist.2. A substance that can combine with a receptor on a cell to initiate signal transduction.3. One involved in a struggle or competition.
[Late Latin agōnista, contender, from Greek agōnistēs, from agōn, contest; see agony.]agonist (ˈæɡənɪst) n1. (Physiology) any muscle that is opposed in action by another muscle. Compare antagonist22. a competitor, as in an agon[C17: from Greek agōn agon]ag•o•nist (ˈæg ə nɪst)
n. 1. a person engaged in a contest, conflict, struggle, etc., esp. the protagonist in a literary work. 2. a person who is torn by inner conflict. 3. a contracting muscle whose action is opposed by another muscle. Compare antagonist (def. 3). 4. a chemical substance capable of activating a receptor to induce a full or partial pharmacological response. Compare antagonist (def. 5). [1620–30; < Late Latin agōnista < Greek agōnistḗs contestant =agṓn agon + -istēs -ist] ag·o·nist (ăg′ə-nĭst) A muscle that actively contracts to produce a desired movement. Compare antagonist.agonistone who contends for a prize in public games. — agonistic, agonistical, adj.See also: AthleticsThesaurus| Noun | 1. |  agonist - the principal character in a work of fictionprotagonistantihero - a protagonist who lacks the characteristics that would make him a hero (or her a heroine) | | 2. |  agonist - someone involved in a contest or battle (as in an agon)contestant - a person who participates in competitionsadversary, antagonist, opposer, resister, opponent - someone who offers opposition | | 3. |  agonist - a muscle that contracts while another relaxes; "when bending the elbow the biceps are the agonist"antagonistic muscle - (physiology) a muscle that opposes the action of another; "the biceps and triceps are antagonistic muscles" | | 4. | agonist - (biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reactiondrug - a substance that is used as a medicine or narcoticbiochemistry - the organic chemistry of compounds and processes occurring in organisms; the effort to understand biology within the context of chemistry |
Translationsagonist
agonist[′ag·ə‚nist] (biochemistry) A chemical substance that can combine with a cell receptor and cause a reaction or create an active site. (physiology) A contracting muscle that is resisted or counteracted by another muscle, called an antagonist, with which it is paired. agonist
agonist [ag´o-nist] muscle" >agonistic muscle.in pharmacology, a drug that has affinity for the cellular receptors of another drug or natural substance and that produces a physiological effect.ag·o·nist (ag'on-ist), 1. Denoting a muscle in a state of contraction, with reference to its opposing muscle, or antagonist. 2. A drug capable of combining with receptors to initiate drug actions; it possesses affinity and intrinsic activity. [G. agōn, a contest] agonist (ăg′ə-nĭst)n.1. Physiology A contracting muscle that is resisted or counteracted by another muscle, the antagonist.2. A substance that can combine with a receptor on a cell to initiate signal transduction.Agonist Anatomy Agonist muscle, prime mover. A muscle that causes a particular movement to occur, creating a normal range of movement in a joint by contracting; a muscle which moves in one general direction.
Molecular biology A ligand which binds a receptor at a site adjacent to the active site.
Pharmacology Agonist medication. A chemical entity that does not naturally occur in the body and acts on one or more receptors (e.g., mu, delta, and kappa opiate receptors) by structural mimicry of the receptors’ natural ligand(s). It may be an agonist or partial agonist for a particular receptor, promoting a receptor-mediated biological response, often by competing with another substance (usually the natural or native substance) at the same receptor. A partial agonist produces less than the maximum effect even if given in a concentration sufficient to bind with all available receptors.agonist Pharmacology A substance that promotes a receptor-mediated biologic response, often by competing with another substance at the same receptor. Cf Antagonist. ag·o·nist (ag'ŏn-ist) 1. A muscle (or group of muscles) whose contraction produces a specific action with reference to its antagonist muscle (or muscles). 2. A drug capable of combining with receptors to initiate drug actions; it possesses affinity and intrinsic activity. [G. agōn, a contest]agonist 1. A molecule, such as a HORMONE, NEUROTRANSMITTER or drug, that attaches (binds) to a cell receptor site to produce an effect on the cell. Many drugs are agonists having an effect similar or identical to natural body agonists. Other drugs act on the receptor in a blocking role and are antagonists. An antagonist is a molecule that interferes with or prevents the action of the agonist. 2. A contracting muscle that is opposed by contraction of another associated muscle, the antagonist. agonist - a substance capable of binding to a molecular target on the cell surface (RECEPTOR) to elicit a biological response. Examples include HORMONES and DRUGS.
- a muscle which initiates a response or change in position of a body part acting against an ANTAGONISTIC MUSCLE.
AgonistA medication that has an affinity for and stimulates the activity of cell receptors that are normally stimulated by naturally occurring substances, including melatonin.Mentioned in: Glaucoma, Jet Lag, Pituitary Tumors, Platelet Aggregation Testagonist 1. An agonistic muscle. 2. A substance (e.g. a drug, hormone or neurotransmitter) that binds with a cell receptor to initiate a physiological response similar to that produced by the natural neurotransmitter or hormone. Example: pilocarpine, which mimics the effect of acetylcholine acting on cholinergic receptors. See antagonist.ag·o·nist (ag'ŏn-ist) 1. Denoting a muscle in a state of contraction, with reference to its opposing muscle, or antagonist. 2. A drug capable of combining with receptors to initiate drug actions; it possesses affinity and intrinsic activity. [G. agōn, a contest]agonist
Related to agonist: Agonist muscle, Dopamine agonistSynonyms for agonistnoun the principal character in a work of fictionSynonymsRelated Wordsnoun someone involved in a contest or battle (as in an agon)Related WordsAntonyms- adversary
- antagonist
- opposer
- resister
- opponent
noun a muscle that contracts while another relaxesRelated Wordsnoun (biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reactionRelated Words |