ancrod


ancrod

 [ang´krod] a proteinase obtained from the venom of the Malayan pit viper Agkistrodon rhodostoma, acting specifically on fibrinogen; used as an anticoagulant in the treatment of retinal vein occlusion and deep vein thrombosis and to prevent postoperative rethrombosis.

an·crod

(an'krod), A fraction obtained from the venom of the Malayan pit viper, Agkistrodon rhodostoma, which contains a fibrinogen-splitting enzyme; produces hypofibrinogenemia and diminution of both whole blood and plasma viscosity for improvement of the rheologic properties of blood, and is used in treatment of chronic peripheral vascular disease.

ancrod

A protease occurring in the venom of the Malaysian pit viper Agkistrodon rhodostoma . The enzyme removes fibrinogen from the circulating blood without converting it to fibrin. It does not cause platelet aggregation and is used by Chinese doctors to treat STROKE. Trials have suggested that it should not be used after the first three hours.