copolymer-1

copolymer-1

acetate salt of a mixture of synthetic polypeptides composed of four amino acids; used to reduce the relapse rate with relapsing-remitting multiple sclerosis.

co·pol·y·mer-1

(kō'pol'i-mĕr) Acetate salt of a mixture of synthetic polypeptides composed of four amino acids; used to reduce the relapse rate with relapsing-remitting multiple sclerosis.

copolymer-1

A mixture of synthetic random polypeptides made from the amino acids alanine, glutamic acid, lysine and tyrosine that has been found to reduce the relapse rate in MULTIPLE SCLEROSIS. Research suggests that the drug can reduce the relapse rate, in patients subject to relapses, from 75 per cent to 66 per cent. The drug is believed to act on helper T cells so as to promote cloning of those whose CYTOKINES are mainly B cell antibody-stimulating (Th-2) rather than those whose cytokines have a mainly inflammatory and destructive effect (Th-1). A brand name is Copaxone.