| 释义 |
dysplastic nevus syndrome dys·plas·tic ne·vusa nevus exceeding 5 mm in diameter, with irregular, indistinct, or notched borders and mixed tan-to-black and pink-to-red color. Microscopically these are basally nested and scattered intraepidermal melanocytes with hyperchromatic nuclei larger than those of basal keratinocytes. If multiple and associated with a family history of melanoma, these nevi have a high risk of malignant change, but isolated dysplastic nevi in the absence of a family history of melanoma are less frequently premalignant.
See also: malignant mole syndrome. Synonym(s): dysplastic nevus syndrome See: dysplastic nevus syndrome.dys·plas·tic ne·vus syn·drome (dis-plas'tik nē'vŭs sin'drōm) Clinically atypical nevi having variable pigmentation and ill-defined borders, with an increased risk for development of cutaneous malignant melanoma; biopsies show melanocytic dysplasia. Dysplastic nevus syndromeA familial syndrome characterized by the presence of multiple atypical appearing moles, often at a young age.Mentioned in: Malignant Melanoma |