dystrophic calcification


calcification

 [kal″sĭ-fĭ-ka´shun] the deposit of calcium salts, mostly calcium phosphate, in body tissues. The normal absorption of calcium is facilitated by parathyroid hormone and by vitamin D. When there are increased amounts of parathyroid hormone in the blood (as in hyperparathyroidism), there is deposition of calcium in the alveoli of the lungs, the renal tubules, the thyroid gland, the gastric mucosa, and the arterial walls. Normally calcium is deposited in the bone matrix to insure stability and strength of the bone and in growing teeth.dystrophic calcification the deposition of calcium in abnormal tissue, such as scar tissue or atherosclerotic plaques, without abnormalities of blood calcium.eggshell calcification deposition of a thin layer of calcium around a thoracic lymph node, often seen in silicosis.

dys·tro·phic cal·ci·fi·ca·tion

calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules.

dystrophic calcification

The combination of fat necrosis and caseating necrosis, resulting in the focal deposition of hydroxyapatite crystals in previously damaged tissues–eg, heart valves, scars, foci of TB and atherosclerotic blood vessels–arising in mitochondria, calcification in hyperparathyroidism which develops in the basement membrane of the renal tubules; DC may occur without hypercalcemia or defects of calcium metabolism

dys·tro·phic cal·ci·fi·ca·tion

(dis-trō'fik kal'si-fi-kā'shŭn) Calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules.

dys·tro·phic cal·ci·fi·ca·tion

(dis-trō'fik kal'si-fi-kā'shŭn) Calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules.