giant cell granuloma

gi·ant cell gran·u·lo·ma

a nonneoplastic lesion characterized by a proliferation of granulation tissue containing numerous multinucleated giant cells; it occurs in the gingiva and alveolar mucosa (occasionally in other soft tissues) where it presents as a soft red-blue hemorrhagic nodular swelling; it also occurs within the mandible or maxilla as a unilocular or multilocular radiolucency; microscopically similar lesions occur in the tubular bones of the hands and feet, are considered neoplastic and may have a malignant course. Identical bony lesions may be seen in hyperparathyroidism and cherubism.
See also: giant cell tumor of bone.
Synonym(s): giant cell epulis, reparative giant cell granuloma
(1) Central giant cell granuloma
(2) Peripheral giant cell granuloma

gi·ant cell gran·u·lo·ma

(jī'ănt sel gran'yū-lō'mă) A nonneoplastic lesion characterized by a proliferation of granulation tissue containing numerous multinucleated giant cells; it occurs on the gingiva and alveolar mucosa (occasionally on other soft tissues) where it presents as a soft red-blue hemorrhagic nodular swelling; it also occurs within the mandible or maxilla as a unilocular or multilocular radiolucency. Identical bony lesions may be seen in hyperparathyroidism and cherubism.
See also: giant cell tumor of bone
Compare: giant cell fibroma

gi·ant cell gran·u·lo·ma

(jī'ănt sel gran'yū-lō'mă) Nonneoplastic lesion characterized by a proliferation of granulation tissue containing numerous multinucleated giant cells; occurs in gingiva and alveolar mucosa (occasionally in other soft tissues) where it presents as a soft red-blue hemorrhagic nodular swelling; also occurs within the mandible or maxilla as a unilocular or multilocular radiolucency.