giant cell hepatitis

ne·o·na·tal hep·a·ti·tis

hepatitis in the neonatal period presumed to be due to any of a variety of causes, chiefly viral; characterized by direct and indirect bilirubinemia, hepatocellular degeneration, and appearance of multinucleated giant cells; may be difficult to distinguish from biliary atresia, but is more likely to end with recovery, although cirrhosis may develop. Synonym(s): giant cell hepatitis

A nonspecific reaction of the newborn liver to increased conjugated hyperbilirubinemia, which occurs with intra- or extrahepatic biliary atresia, erythroblastosis fetalis, TORCH (toxoplasmosis, rubella, cytomegalovirus, herpes simplex) and other in utero and neonatal infections (e.g., coxsackie, hepatitis, Escherichia coli infection, syphilis) and metabolic defects (e.g., a1-antitrypsin deficiency; cystic fibrosis; hereditary fructose intolerance; galactosemia; tyrosinosis requiring parenteral nutrition; choledocal cysts, idiopathic, congenital hepatic fibrosis, trisomy 18 and Byler’s, Lucey-Driscoll, Niemann-Pick and Zellweger’s diseases)

giant cell hepatitis

Giant cell transformation of liver Neonatology A nonspecific reaction of the newborn liver to ↑ conjugated hyperbilirubinemia; conjugated BR is ↑ in infants with intra- or extrahepatic biliary atresia, erythroblastosis fetalis, TORCH–toxoplasmosis, rubella, CMV, HS, and other in utero and neonatal infections–eg, coxsackie, hepatitis, E coli, syphilis, metabolic defects–eg, α₁-antitrypsin deficiency, cystic fibrosis, hereditary fructose intolerance, galactosemia, parenteral nutrition and tyrosinosis, choledocal cysts, idiopathic, congenital hepatic fibrosis, Byler's disease, Lucy-Driscoll disease, Niemann-Pick disease, trisomy 18, and Zellweger's disease. Cf Syncytial giant cell hepatitis.

单词	giant cell hepatitis
释义	giant cell hepatitis ne·o·na·tal hep·a·ti·tis hepatitis in the neonatal period presumed to be due to any of a variety of causes, chiefly viral; characterized by direct and indirect bilirubinemia, hepatocellular degeneration, and appearance of multinucleated giant cells; may be difficult to distinguish from biliary atresia, but is more likely to end with recovery, although cirrhosis may develop. Synonym(s): giant cell hepatitis A nonspecific reaction of the newborn liver to increased conjugated hyperbilirubinemia, which occurs with intra- or extrahepatic biliary atresia, erythroblastosis fetalis, TORCH (toxoplasmosis, rubella, cytomegalovirus, herpes simplex) and other in utero and neonatal infections (e.g., coxsackie, hepatitis, Escherichia coli infection, syphilis) and metabolic defects (e.g., a1-antitrypsin deficiency; cystic fibrosis; hereditary fructose intolerance; galactosemia; tyrosinosis requiring parenteral nutrition; choledocal cysts, idiopathic, congenital hepatic fibrosis, trisomy 18 and Byler’s, Lucey-Driscoll, Niemann-Pick and Zellweger’s diseases) giant cell hepatitis Giant cell transformation of liver Neonatology A nonspecific reaction of the newborn liver to ↑ conjugated hyperbilirubinemia; conjugated BR is ↑ in infants with intra- or extrahepatic biliary atresia, erythroblastosis fetalis, TORCH–toxoplasmosis, rubella, CMV, HS, and other in utero and neonatal infections–eg, coxsackie, hepatitis, E coli, syphilis, metabolic defects–eg, α₁-antitrypsin deficiency, cystic fibrosis, hereditary fructose intolerance, galactosemia, parenteral nutrition and tyrosinosis, choledocal cysts, idiopathic, congenital hepatic fibrosis, Byler's disease, Lucy-Driscoll disease, Niemann-Pick disease, trisomy 18, and Zellweger's disease. Cf Syncytial giant cell hepatitis.
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