| 释义 |
general paralysis of the insane
general paralysis of the insane n (Pathology) a disease of the central nervous system: a late manifestation of syphilis, often occurring up to 15 years after the original infection, characterized by mental deterioration, speech defects, and progressive paralysis. Abbreviation: GPI Also called: general paresis or dementia paralytica general paralysis of the insane
general paralysis of the insane (GPI) A now rare form of dementia from SYPHILIS of the nervous system. GPI was a feature of the third (tertiary) stage of untreated syphilis and occurred 10–20 years after infection in a small proportion of cases. The condition is characterized by delusions of grandeur, mania and sometimes delusions of persecution.AcronymsSeeGPI |