glucose-6-phosphate dehydrogenase (G6PD) deficiency

glu·cose-6-phos·phate de·hy·dro·gen·ase (G6PD) de·fi·cien·cy

(glū'kōs fos'fāt dē-hī-droj'ĕ-nās dĕ-fish'ĕn-sē) Congenital deficiency of glucose-6-phosphate dehydrogenase, an enzyme important for maintaining cellular concentrations of reduced nucleotides; can cause a variety of anemias, including favism, primaquine sensitivity and other drug-sensitivity anemias, anemia of the newborn, and chronic nonspherocytic hemolytic anemia.