bergamottin

(bĕr-ga-mot'in), One of a group of chemicals found in grapefruit juice (collectively called furanocoumarins), which inhibit CYP450 3A4.
See also: furanocoumarin.

bergamottin

A natural furanocoumarin found in oil of bergamot, grapefruit juice as well as other citrus fruits. Bergamottin and its related metabolites are of pharmacological interest because they inhibit certain cytochrome P450 enzymes, especially CYP3A4, which metabolises an array of drugs from antihistamines to antihypertensives, explaining why certain drugs have greater bioavailability in people who eat a large amount of grapefruit.

单词	bergamottin
释义	bergamottin bergamottin (bĕr-ga-mot'in), One of a group of chemicals found in grapefruit juice (collectively called furanocoumarins), which inhibit CYP450 3A4. See also: furanocoumarin. bergamottin A natural furanocoumarin found in oil of bergamot, grapefruit juice as well as other citrus fruits. Bergamottin and its related metabolites are of pharmacological interest because they inhibit certain cytochrome P450 enzymes, especially CYP3A4, which metabolises an array of drugs from antihistamines to antihypertensives, explaining why certain drugs have greater bioavailability in people who eat a large amount of grapefruit.
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