glucuronic acid

(ˌɡluːkjʊˈrɒnɪk) n (Chemistry) chem a soluble compound derived from glucose. Formula C6H10O7

glu′cu•ron′ic ac′id

(ˈglu kyəˈrɒn ɪk, ˌglu-)
n. an acid, C₆H₁₀O₇, formed by the oxidation of glucose, found combined with other products of metabolism in the blood and urine. [1910–15]

Translations

Glucuronic Acid

glucuronic acid

[¦glü·kyə¦rän·ik ′as·əd] (biochemistry) C₆H₁₀O₇ An acid resulting from oxidation of the CH₂OH radical ofD-glucose to COOH; a component of many polysaccharides and certain vegetable gums. Also known as glycuronic acid.

Glucuronic Acid

one of the uronic acids, COH(CHOH)₄COOH; it is formed in the body from glucose when the latter is oxidized by a primary alcohol group. It is optically active and dissolves readily in water. Melting point, 167°-172° C. D-glucuronic acid is widespread in the animal and vegetable worlds and is a component of acid mucopolysaccharides, some bacterial polysaccharides, triterpenoid saponins, hemicellulose, and gums. Free glucuronic acid is found in blood and urine in small quantities. Certain metabolic products, including some toxic products (phenol and cresol), as well as many medications, are discharged with the urine in the form of sister compounds of glucuronic acid (glucuronides). Conversions of glucuronic acid in all animals except the monkey and guinea pig, as well as in humans, lead to the biosynthesis of ascorbic acid. Body fluids and tissues of animals (especially the liver, kidneys, and spleen, and also malignant tumors) and bacterial and plant tissues contain the enzyme β-glucuronidase, which catalyzes the hydrolysis of β-glucuronides to free glucuronic acid and the corresponding aglycon.

G. A. SOLOV’EVA

glucuronic acid

[gloo″ku-ron´ik] a uronic acid formed by oxidation of C-6 of glucose to a carboxy group; it occurs in proteoglycans (mucopolysaccharides), and is important in the conjugation of xenobiotics; it is conjugated to many poisons and drugs by the liver, forming glucuronides, which markedly decreases their toxicity and enhances their excretion by the liver, intestine, and kidney.

glu·cu·ron·ic ac·id

(glū'kū-ron'ik as'id), The uronic acid of glucose in which C-6 is oxidized to a carboxyl group; the d-isomer detoxicates or inactivates various substances (for example, benzoic acid, phenol, camphor, and the female sex hormones) undergoing conjugation with such substances in the liver, the glucuronides so formed being excreted in the urine.

glu·cu·ron·ic ac·id

(glū'kyūr-on'ik as'id) The uronic acid of glucose in which C-6 is oxidized to a carboxyl group; the d-isomer detoxicates or inactivates various substances (e.g., benzoic acid, phenol, camphor, and the female sex hormones), the glucuronides so formed being excreted in the urine.

glucuronic acid

A substance formed from glucose that combines with many body waste products to form glycosides that are excreted in the urine.

单词	glucuronic acid
释义	glucuronic acid glucuronic acid (ˌɡluːkjʊˈrɒnɪk) n (Chemistry) chem a soluble compound derived from glucose. Formula C6H10O7 glu′cu•ron′ic ac′id (ˈglu kyəˈrɒn ɪk, ˌglu-) n. an acid, C₆H₁₀O₇, formed by the oxidation of glucose, found combined with other products of metabolism in the blood and urine. [1910–15] Translations Glucuronic Acid glucuronic acid [¦glü·kyə¦rän·ik ′as·əd] (biochemistry) C₆H₁₀O₇ An acid resulting from oxidation of the CH₂OH radical ofD-glucose to COOH; a component of many polysaccharides and certain vegetable gums. Also known as glycuronic acid. Glucuronic Acid one of the uronic acids, COH(CHOH)₄COOH; it is formed in the body from glucose when the latter is oxidized by a primary alcohol group. It is optically active and dissolves readily in water. Melting point, 167°-172° C. D-glucuronic acid is widespread in the animal and vegetable worlds and is a component of acid mucopolysaccharides, some bacterial polysaccharides, triterpenoid saponins, hemicellulose, and gums. Free glucuronic acid is found in blood and urine in small quantities. Certain metabolic products, including some toxic products (phenol and cresol), as well as many medications, are discharged with the urine in the form of sister compounds of glucuronic acid (glucuronides). Conversions of glucuronic acid in all animals except the monkey and guinea pig, as well as in humans, lead to the biosynthesis of ascorbic acid. Body fluids and tissues of animals (especially the liver, kidneys, and spleen, and also malignant tumors) and bacterial and plant tissues contain the enzyme β-glucuronidase, which catalyzes the hydrolysis of β-glucuronides to free glucuronic acid and the corresponding aglycon. G. A. SOLOV’EVA glucuronic acid glucuronic acid [gloo″ku-ron´ik] a uronic acid formed by oxidation of C-6 of glucose to a carboxy group; it occurs in proteoglycans (mucopolysaccharides), and is important in the conjugation of xenobiotics; it is conjugated to many poisons and drugs by the liver, forming glucuronides, which markedly decreases their toxicity and enhances their excretion by the liver, intestine, and kidney. glu·cu·ron·ic ac·id (glū'kū-ron'ik as'id), The uronic acid of glucose in which C-6 is oxidized to a carboxyl group; the d-isomer detoxicates or inactivates various substances (for example, benzoic acid, phenol, camphor, and the female sex hormones) undergoing conjugation with such substances in the liver, the glucuronides so formed being excreted in the urine. glu·cu·ron·ic ac·id (glū'kyūr-on'ik as'id) The uronic acid of glucose in which C-6 is oxidized to a carboxyl group; the d-isomer detoxicates or inactivates various substances (e.g., benzoic acid, phenol, camphor, and the female sex hormones), the glucuronides so formed being excreted in the urine. glucuronic acid A substance formed from glucose that combines with many body waste products to form glycosides that are excreted in the urine. ThesaurusSeeacid
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