acute tubulointerstitial nephritis

A condition characterised by tubular damage leading to renal tubular dysfunction, which is generally reversible and is attributed to the regenerative capacity of tubules with preserved basement membrane.
Aetiology
Drugs—NSAIDs, antibiotics, rifampin, allopurinol, IFN-alpha, PPI inhibitors, TINU (tubuloinerstitial nephritis and bilateral uveitis); granulomatous inflammation—e.g., sarcoidosis.
Clinical findings
Patients generally present abruptly with rash, fever, eosinophilia, eosinophiluria, and elevated IgE. In cases linked to NSAIDs, acute disease follows months of NSAID use.

Mechanism
Hypersensivity reaction to drugs or bacteria/viruses.

单词	acute tubulointerstitial nephritis
释义	acute tubulointerstitial nephritis acute tubulointerstitial nephritis A condition characterised by tubular damage leading to renal tubular dysfunction, which is generally reversible and is attributed to the regenerative capacity of tubules with preserved basement membrane. Aetiology Drugs—NSAIDs, antibiotics, rifampin, allopurinol, IFN-alpha, PPI inhibitors, TINU (tubuloinerstitial nephritis and bilateral uveitis); granulomatous inflammation—e.g., sarcoidosis. Clinical findings Patients generally present abruptly with rash, fever, eosinophilia, eosinophiluria, and elevated IgE. In cases linked to NSAIDs, acute disease follows months of NSAID use. Mechanism Hypersensivity reaction to drugs or bacteria/viruses. AcronymsSeeATIN
随便看	know you by sight know you from a bar of soap know you inside out know you in the biblical sense know you like a book know your acronyms know your beans know your business know your client know-your-client know your customer know-your-customer know your customer manual know your customer rule know-your-customer rule know your customer rules know your enemy know your financial advisor know your government know your history know your ibm know your meme know your midwife know your money know your north pennines