gammopathy

[gam-mop´ah-the] abnormal proliferation of the lymphoid cells producing immunoglobulins" >immunoglobulins; the gammopathies include multiple myeloma" >multiple myeloma, macroglobulinemia" >macroglobulinemia, and Hodgkin's disease. Called also gammaglobulinopathy.monoclonal g's plasma cell dyscrasias.

gam·mop·a·thy

(gă-mop'ă-thē), A primary disturbance in immunoglobulin synthesis.

gammopathy

An abnormal ↑ in immunoglobulin production; monoclonal gammopathies–MGs are usually malignant Examples Myeloma, Waldenström's disease, CLL, heavy-chain disease, but may also be benign, appearing in amyloidosis and MG of undetermined significance; polyclonal gammopathies are usually benign and appear in inflammatory conditions–eg, angioimmunoblastic lymphadenopathy, cirrhosis, leishmaniasis, rheumatoid arthritis, SLE, TB. Note: Polyclonal gammopathies may occur as epiphenomena in lymphomas, Hodgkin's disease, metastatic adenoCA. See Biclonal gammopathy, Monoclonal gammopathy of undetermined significance.

gam·mop·a·thy

(gă-mop'ă-thē) A primary disturbance in immunoglobulin synthesis.

gammopathy

Any abnormality, in quality or quantity, of the IMMUNOGLOBULINS present in the blood. Benign monoclonal gammopathy is an abnormal production of a single clone of an immunoglobulin. Gammopathies are associated with MYELOMATOSIS.

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Words related to gammopathy

noun a disturbance in the synthesis of immunoglobulins

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