| 释义 |
Gonadotrophic Hormones
Gonadotrophic Hormones (gonadotrophins), hormones formed by the anterior lobe of the pituitary that regulate the endocrine function of the gonads. The gonadotrophic hormones include follicle-stimulating hormone (prolan A), luteinizing hormone (prolan B, interstial-cell-stimulating hormone, metakentrin), and luteo-tropic hormone (prolactin, mammotropin, mammogen). In females the gonadotrophic hormones stimulate maturation of the egg cells, ovulation, formation of the corpus luteum (in mammals), and the secretion of estrogens; in males they promote spermatogenesis, the growth of interstitial cells, and the secretion of testosterone. Chorionic gonadotrophin (containing predominantly luteinizing hormone), which is obtained from the urine of pregnant women, and a gonadotrophin from the blood serum of pregnant mares (containing predominantly follicle-stimulating hormone) are used for therapeutic purposes (for example, in disturbances of the menstrual cycle, infertility, hypogenitalism, and obesity). gonadotrophic hormones
gonadotrophic hormones PITUITARY GLAND hormones that stimulate the testicles and the ovaries to produce sperms (spermatozoa), eggs (ova) and sex hormones. Follicle stimulating hormone promotes the growth and development of the eggs ova and sperms, and luteinizing hormone prompts the production of sex hormones. Gonadotrophic hormones are used as drugs to treat infertility, delayed puberty and underdevelopment of the gonads.gonadotrophin or gonadotrophic hormones hormones secreted by the anterior lobe of the PITUITARY GLAND and in some mammals, once pregnancy is under way, by the PLACENTA. FSH and LH are produced by all TETRAPODS though FSH appears to be absent in fish. LTH (Luteotrophin) is present in rats and maintains the CORPUS LUTEUM though it is absent in other mammals. Prolactin is present in some vertebrates and controls milk production (LTH is a form of prolactin). Pituitary output is controlled by the hypothalamus. Gonadotrophins influence other glands connected with reproduction, controlling the activity of the gonads, the onset of sexual maturity, OESTROUS CYCLES, breeding rhythms and LACTATION. See also HCG. |