| 单词 | gemin8 |
| 释义 | GEMIN8GEMIN8A gene on chromosome Xp22.2 that encodes gem-associated protein 8, a member of the survival of motor neuron (SMN) complex. The SMN complex plays a key role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. GEMIN8 binds directly to SMN1 and to the GEMIN6-GEMIN7 heterodimer, mediating their interaction. |
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