fructose-bisphosphatase

fruc·tose-bis·phos·pha·tase

(fruk'tōs bis-fos'fă-tās), A hydrolase that catalyzes conversion of fructose 1,6-bisphosphate to d-fructose 6-phosphate and orthophosphate in gluconeogenesis; AMP is an allosteric inhibitor; fructose-bisphosphatase deficiency results in problems with impaired gluconeogenesis; there is a similar enzyme that acts on fructose 2,6-bisphosphate.