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ghrelin
ghrel·in G5120225 (grĕl′ən)n. A hormone that is secreted by cells in the stomach and promotes hunger before an expected meal, decreases in amount after eating, and promotes secretion of growth hormone.
[Coined by its discoverers from ghrē-, reconstructed Proto-Indo-European root of English grow; see grow + -in (probably influenced by g(rowth)-h(ormone)-rel(easing peptide), a description of ghrelin's function and chemical composition).]ghrelin (ˈɡrɛlɪn) n (Biochemistry) a hormone produced in the body that stimulates appetite[C20: from g(rowth) h(ormone) rel(easing) + -in]Thesaurus| Noun | 1. | ghrelin - a gastrointestinal hormone produced by epithelial cells lining the fundus of the stomach; appears to be a stimulant for appetite and feeding, but is also a strong stimulant of growth hormone secretion from the anterior pituitarygastrointestinal hormone, GI hormones - hormones that affect gastrointestinal functioning |
ghrelin
ghrel·in (grel'in), A naturally occurring 28-amino acid gut-brain growth hormone releasing peptide (GHRP) that is expressed mainly in the stomach and possibly in the hypothalamus. Fasting and hypoglycemia increase ghrelin levels and circulating ghrelin levels are decreased in chronic obesity, following acute caloric intake and in states of positive energy balance. Acute administration of ghrelin to humans induces a feeling of hunger. Ghrelin binds to ghrelin-receptors in the anterior pituitary and possibly in the mediobasal and mediolateral hypothalamus to stimulate growth hormone release and to regulate energy homeostasis. Serum levels of ghrelin are measurably higher in patients who have lost weight through dietary measures. [growth hormone release + -in] ghrelin (grĕl′ən)n. A hormone that is secreted by cells in the stomach and promotes hunger before an expected meal, decreases in amount after eating, and promotes secretion of growth hormone.ghrel·in (grel'in) A peptide hormone secreted by endocrine cells in the gastrointestinal tract. Acts as a growth hormone secretagogue and as an orexigenic agent mediated by the hypothalamic hormones neuropeptide Y (NPY) and agouti growth-related peptide (AGRP). [growth hormone release + -in]ghrelin A 28-amino acid peptide hormone that stimulates release of growth hormone from the anterior pituitary and has significant effects on appetite and energy balance. The main source of ghrelin is the epithelial cells of the fundus of the empty stomach. Recent studies have shown that, in mice, the hormone also interacts with the hippocampus and appears to improve memory and cognitive function.GhrelinA recently discovered peptide hormone secreted by cells in the lining of the stomach. Ghrelin is important in appetite regulation and maintaining the body's energy balance.Mentioned in: Obesityghrelin
Related to ghrelin: PYYWords related to ghrelinnoun a gastrointestinal hormone produced by epithelial cells lining the fundus of the stomachRelated Words- gastrointestinal hormone
- GI hormones
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