释义 |
hemoglobin CGeorgetown he·mo·glo·bin CGeorgetown , hemoglobin CHarlem [MIM*141900.0039] two abnormal Hb's, both with the substitution of a valyl residue for a glutamyl residue at the sixth position of the β chain as in Hb S, and in addition, each has a second substitution of an asparaginyl residue for an aspartyl residue at position 73 of the β chain; both types cause sickling of erythrocytes similar to Hb S. |