hemoglobin E

he·mo·glo·bin E

[MIM*141900.0071] an abnormal Hb with a single β chain substitution, molecular formula α₂^Aβ₂^26Glu→Lys, common in Southeast Asia, especially Thailand; heterozygotes are asymptomatic with 35-45% Hb E; homozygotes have mild to moderate hemolytic anemia with 90-100% Hb E and the remainder Hb F.

hemoglobin E

A hemoglobin molecule in which lysine is substituted for glutamic acid at the 26th position of the beta chain. This variation is found most often in those of Southeast Asian ancestry. See also: hemoglobin

单词	hemoglobin e
释义	DictionarySeehemoglobin hemoglobin E hemoglobin E [′hē·mə‚glō·bən ′ē] (pathology) An abnormal hemoglobin found in people of Southeast Asia, migrating slightly faster than hemoglobin C; in the homozygous form it causes a mild hemolytic anemia with normochromic target cells. hemoglobin E he·mo·glo·bin E [MIM*141900.0071] an abnormal Hb with a single β chain substitution, molecular formula α₂^Aβ₂^26Glu→Lys, common in Southeast Asia, especially Thailand; heterozygotes are asymptomatic with 35-45% Hb E; homozygotes have mild to moderate hemolytic anemia with 90-100% Hb E and the remainder Hb F. hemoglobin E A hemoglobin molecule in which lysine is substituted for glutamic acid at the 26th position of the beta chain. This variation is found most often in those of Southeast Asian ancestry. See also: hemoglobin
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