Definition of derepress in English:
derepress
verbˌdiːrɪˈprɛsˌdēriˈpres
[with object]Biochemistry Genetics Activate (enzymes, genes, etc.) from an inoperative or latent state.
Example sentencesExamples
- In addition, these mutations were able to derepress endogenous genes at HML.
- Most of the genes are derepressed in the absence of a functional hns gene, indicating that H-NS mainly functions as a repressor.
- Starvation for histidine derepresses the entire operon, the longest then known.
- Blocking deacetylation by sodium butyrate or trichostatin A derepresses silent rRNA genes subject to nucleolar dominance.
- About 3% of yeast genes are derepressed in tup1 mutants, as determined by microarray analysis.
Derivatives
noun
Biochemistry Genetics This suggests that glucose derepression is a permissive factor for clonal senescence.
Example sentencesExamples
- This model also predicts that deletion of the Set1 histone methyltransferase would lead to the derepression of subtelomeric genes.
- The importance of the nucleosome in gene regulation is supported by the finding that mutations that alter intracellular levels of histones lead to transcriptional derepression of a variety of genes.
- Indeed, guk1 and hpt1 mutants share several phenotypes (adenine derepression, purine excretion, and 8-azaguanine resistance).
- However, whether derepression of the hTERT gene is the sole requirement for immortalization in all human cell types remained unresolved.