Definition of ganglioside in English:
ganglioside
noun ˈɡaŋɡlɪə(ʊ)sʌɪdˈɡaNGɡlēəˌsīd
Biochemistry Any of a group of complex lipids which are present in the grey matter of the human brain.
Example sentencesExamples
- The condition is due to the absence of an essential enzyme that breaks down a substance called ganglioside, present mainly in the nervous system.
- We have also clarified the binding specificity of gangliosides with proteins depending on the combination of oligosaccharide chain and protein surface modification.
- The most complex of these are the gangliosides, which contain one or more sialic acid residues and thus have a net negative change under physiological conditions.
- There has been strong biochemical evidence that gangliosides are concentrated in these structures.
- This may be explained by the difference in interaction of the tip with the polar zwitterionic PC headgroups and the anionic oligosaccharide headgroups of the ganglioside.
Origin
1940s: from ganglion + -oside (see -ose2, -ide).