Definition of nucleophilic in English:

nucleophilic

adjective ˌnjuːklɪə(ʊ)ˈfɪlɪkˌn(y)o͞oklēōˈfilik

Chemistry

(of a molecule or group) having a tendency to donate electrons or react at electron-poor sites such as protons.
Often contrasted with electrophilic
Example sentencesExamples
- EO is a direct-acting mutagen that reacts with nucleophilic molecules, including DNA, causing gene mutation and chromosome deletions in somatic cells.
- One highly characteristic reaction of aldehydes and ketones is nucleophilic addition to the carbon-oxygen double bond.
- The most common substitution reactions of compounds of non-metallic elements are nucleophilic and electrophilic substitution.
- In the case of aldehydes and ketones containing carbonyl groups, the highly nucleophilic Grignard reagent contributes its electron pair to form a bond with the carbon atom.
- Methyl lithium is very reactive and acts as a nucleophilic methylating reagent to electrophilic functional groups, such as ketones.

Derivatives

nucleophile

noun ˈnjuːklɪə(ʊ)fʌɪlˈn(j)uklioʊˌfaɪl

Chemistry

A molecule or substance that has a tendency to donate electrons or react at electron-poor sites such as protons.
nucleophiles are produced in the formation of acids and bases
Example sentencesExamples
- In a similar way, both hydroxide ions and water molecules may act as nucleophiles by reacting with alkyl halides to produce alcohols.
- Unlike hydrocarbon based aromatics, which react most readily with electrophiles, perfluoro-aromatics and heterocyclic ring systems react better with nucleophiles.
- The reactions can involve either anionic nucleophiles such as iodide ion or neutral molecules such as amines.

Definition of nucleophilic in US English:

nucleophilic

adjectiveˌn(y)o͞oklēōˈfilik

Chemistry

(of a molecule or group) having a tendency to donate electrons or react at electron-poor sites such as protons.
Often contrasted with electrophilic
Example sentencesExamples
- EO is a direct-acting mutagen that reacts with nucleophilic molecules, including DNA, causing gene mutation and chromosome deletions in somatic cells.
- Methyl lithium is very reactive and acts as a nucleophilic methylating reagent to electrophilic functional groups, such as ketones.
- One highly characteristic reaction of aldehydes and ketones is nucleophilic addition to the carbon-oxygen double bond.
- In the case of aldehydes and ketones containing carbonyl groups, the highly nucleophilic Grignard reagent contributes its electron pair to form a bond with the carbon atom.
- The most common substitution reactions of compounds of non-metallic elements are nucleophilic and electrophilic substitution.

单词	nucleophilic
释义	Definition of nucleophilic in English: nucleophilic adjective ˌnjuːklɪə(ʊ)ˈfɪlɪkˌn(y)o͞oklēōˈfilik Chemistry (of a molecule or group) having a tendency to donate electrons or react at electron-poor sites such as protons. Often contrasted with electrophilic Example sentencesExamples EO is a direct-acting mutagen that reacts with nucleophilic molecules, including DNA, causing gene mutation and chromosome deletions in somatic cells. One highly characteristic reaction of aldehydes and ketones is nucleophilic addition to the carbon-oxygen double bond. The most common substitution reactions of compounds of non-metallic elements are nucleophilic and electrophilic substitution. In the case of aldehydes and ketones containing carbonyl groups, the highly nucleophilic Grignard reagent contributes its electron pair to form a bond with the carbon atom. Methyl lithium is very reactive and acts as a nucleophilic methylating reagent to electrophilic functional groups, such as ketones. Derivatives nucleophile noun ˈnjuːklɪə(ʊ)fʌɪlˈn(j)uklioʊˌfaɪl Chemistry A molecule or substance that has a tendency to donate electrons or react at electron-poor sites such as protons. nucleophiles are produced in the formation of acids and bases Example sentencesExamples In a similar way, both hydroxide ions and water molecules may act as nucleophiles by reacting with alkyl halides to produce alcohols. Unlike hydrocarbon based aromatics, which react most readily with electrophiles, perfluoro-aromatics and heterocyclic ring systems react better with nucleophiles. The reactions can involve either anionic nucleophiles such as iodide ion or neutral molecules such as amines. Definition of nucleophilic in US English: nucleophilic adjectiveˌn(y)o͞oklēōˈfilik Chemistry (of a molecule or group) having a tendency to donate electrons or react at electron-poor sites such as protons. Often contrasted with electrophilic Example sentencesExamples EO is a direct-acting mutagen that reacts with nucleophilic molecules, including DNA, causing gene mutation and chromosome deletions in somatic cells. Methyl lithium is very reactive and acts as a nucleophilic methylating reagent to electrophilic functional groups, such as ketones. One highly characteristic reaction of aldehydes and ketones is nucleophilic addition to the carbon-oxygen double bond. In the case of aldehydes and ketones containing carbonyl groups, the highly nucleophilic Grignard reagent contributes its electron pair to form a bond with the carbon atom. The most common substitution reactions of compounds of non-metallic elements are nucleophilic and electrophilic substitution.
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