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单词 puromycin
释义

Definition of puromycin in English:

puromycin

noun ˌpjʊərə(ʊ)ˈmʌɪsɪnˌpyo͝orōˈmīsin
mass nounMedicine
  • An antibiotic used to treat sleeping sickness and amoebic dysentery.

    This antibiotic is produced by the bacterium Streptomyces alboniger

    Example sentencesExamples
    • This was transfected with a transgene encoding resistance to puromycin, and a predominantly negative, puromycin-resistant colony was isolated.
    • Clonal cell lines were expanded in complete DMEM containing 7.5 g/ml puromycin and were transferred to serum free DMEM approximately 24 hours prior to harvesting.
    • Cells were exposed to the retrovirus for 24 hr, followed by media change and a 24-hr recovery period prior to selection of retroviral linked selection markers (neomycin, puromycin, or hygromycin).
    • Determination of the puromycin dose: Puromycin was used at 100 g/ml on wild-type starved cultures.
    • If it were, say puromycin, the results of half the lab would be ruined for a year.

Origin

1950s: from purine + -mycin.

 
 

Definition of puromycin in US English:

puromycin

nounˌpyo͝orōˈmīsin
Medicine
  • An antibiotic used to treat sleeping sickness and amoebic dysentery.

    This antibiotic is produced by the bacterium Streptomyces alboniger

    Example sentencesExamples
    • This was transfected with a transgene encoding resistance to puromycin, and a predominantly negative, puromycin-resistant colony was isolated.
    • Cells were exposed to the retrovirus for 24 hr, followed by media change and a 24-hr recovery period prior to selection of retroviral linked selection markers (neomycin, puromycin, or hygromycin).
    • If it were, say puromycin, the results of half the lab would be ruined for a year.
    • Clonal cell lines were expanded in complete DMEM containing 7.5 g/ml puromycin and were transferred to serum free DMEM approximately 24 hours prior to harvesting.
    • Determination of the puromycin dose: Puromycin was used at 100 g/ml on wild-type starved cultures.

Origin

1950s: from purine + -mycin.

 
 
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更新时间:2025/1/11 18:17:12