Definition of puromycin in English:
puromycin
noun ˌpjʊərə(ʊ)ˈmʌɪsɪnˌpyo͝orōˈmīsin
mass nounMedicine An antibiotic used to treat sleeping sickness and amoebic dysentery.
This antibiotic is produced by the bacterium Streptomyces alboniger
Example sentencesExamples
- This was transfected with a transgene encoding resistance to puromycin, and a predominantly negative, puromycin-resistant colony was isolated.
- Clonal cell lines were expanded in complete DMEM containing 7.5 g/ml puromycin and were transferred to serum free DMEM approximately 24 hours prior to harvesting.
- Cells were exposed to the retrovirus for 24 hr, followed by media change and a 24-hr recovery period prior to selection of retroviral linked selection markers (neomycin, puromycin, or hygromycin).
- Determination of the puromycin dose: Puromycin was used at 100 g/ml on wild-type starved cultures.
- If it were, say puromycin, the results of half the lab would be ruined for a year.
Origin
1950s: from purine + -mycin.