Definition of phagosome in English:
phagosome
noun ˈfaɡə(ʊ)səʊmˈfaɡəˌsōm
Biology A vacuole in the cytoplasm of a cell, containing a phagocytosed particle enclosed within a part of the cell membrane.
Example sentencesExamples
- The process of phagocytosis continues until the bacterium is completely internalized, surrounded by membrane in the phagosome.
- We developed a method for simultaneous measurement of average extra- and intracellular oxygen concentrations, which also does not require the presence of phagosomes and therefore can be used in any cell line.
- In the phagosomes, lysosomes are activated and fuse with the apoptotic bodies, bringing on their dissolution.
- After internalization of organisms into phagosomes, secondary lysosomes are fused to form the complete parasitophorus vacuole.
- The researchers engineer a BCG strain that secretes the listeriolysin protein, which punches holes in the membranes of phagosomes where M. tuberculosis is located, allowing better T cell-mediated immunity.
Derivatives
adjective
Biology Failure of mycobacteria to survive in the absence of specific iron uptake system suggests the scarcity of this important nutrient in phagosomal environment 59.
Example sentencesExamples
- We next analysed phagosomal pH in wild-type and Rab27a-deficient dendritic cells.
- The pathogenesis of mycobacterial infection is associated with an ability to interfere with maturation of the phagosomal compartment after ingestion by macrophages.
- Electrons are transferred from cytoplasmic NADPH to oxygen on the phagosomal side of the membrane, generating the so-called reactive oxygen species, e.g., superoxide, hydrogen peroxide, hydroxyl radical, and singlet oxygen.
- The lack of urease C allows phagosomal acidification and provides an ideal pH environment for listeriolysin.