Definition of oligonucleotide in English:
oligonucleotide
noun ˌɒlɪɡə(ʊ)ˈnjuːklɪətʌɪdˌäləɡōˈn(y)o͞oklēətīd
Biochemistry A polynucleotide whose molecules contain a relatively small number of nucleotides.
Example sentencesExamples
- Creation and purification of the double-labeled oligonucleotide is synthetically demanding.
- The purity of the double-stranded oligonucleotides was confirmed by polyacrylamide gel electrophoresis.
- Probes are typically fairly short sequences of DNA nucleotides, called oligonucleotides, made synthetically.
- Intermolecular tetrameric complexes are usually only formed by short oligonucleotides that contain single tracts of contiguous guanines.
- The latter is conjugated to primer oligonucleotides that are pre-annealed to a complementary circular oligonucleotide.
- On single-stranded oligonucleotides, all the guanines are oxidized to the same extent.
- In apoptosis, DNA is degraded into oligonucleotides with a few hundreds of basepairs that subsequently diffuse out of the nucleus.
- This was followed minutes later by the injection of the oligonucleotide complementary to the DNA strand immobilized on sphere S2.
- The unzipping direction (order of nucleotides unzipped) was controlled by the selection of oligonucleotides.
- The unmodified polynucleotides may be DNA, RNA or synthesized oligonucleotides.
- This problem would be enhanced using arrays composed of long oligonucleotides since only RNAs whose protected regions overlap with the oligo sequence would be identified.
- We have been examining the potential use of oligonucleotides to direct nucleotide exchanges in episomal and chromosomal genes.
- The peptides can be linked to a large protein or an oligonucleotide, which may then be carried through the cell membrane.
- The proper orientation and the sequence of the cloned oligonucleotides were checked by nucleotide sequencing.
- For single bulges in RNA oligonucleotides, the conformation usually depends on the nature of the flanking base pairs.
- One important application is gene therapy, where it is necessary to deliver a gene or a synthetic oligonucleotide into the cell.
- In vitro studies on novel DNA structures have mainly involved synthetic oligonucleotides based on naturally occurring sequences.
- Liposomal formulations of genetic drugs such as antisense oligonucleotides and plasmid DNA are difficult to achieve.
- These studies demonstrate that pre-existing cytosine methylation on oligonucleotides…
- The latter is generally restricted to oligonucleotides but offers higher specificity.
Definition of oligonucleotide in US English:
oligonucleotide
nounˌäləɡōˈn(y)o͞oklēətīd
Biochemistry A polynucleotide whose molecules contain a relatively small number of nucleotides.
Example sentencesExamples
- In apoptosis, DNA is degraded into oligonucleotides with a few hundreds of basepairs that subsequently diffuse out of the nucleus.
- For single bulges in RNA oligonucleotides, the conformation usually depends on the nature of the flanking base pairs.
- This was followed minutes later by the injection of the oligonucleotide complementary to the DNA strand immobilized on sphere S2.
- On single-stranded oligonucleotides, all the guanines are oxidized to the same extent.
- The latter is generally restricted to oligonucleotides but offers higher specificity.
- Liposomal formulations of genetic drugs such as antisense oligonucleotides and plasmid DNA are difficult to achieve.
- This problem would be enhanced using arrays composed of long oligonucleotides since only RNAs whose protected regions overlap with the oligo sequence would be identified.
- We have been examining the potential use of oligonucleotides to direct nucleotide exchanges in episomal and chromosomal genes.
- The purity of the double-stranded oligonucleotides was confirmed by polyacrylamide gel electrophoresis.
- Probes are typically fairly short sequences of DNA nucleotides, called oligonucleotides, made synthetically.
- The proper orientation and the sequence of the cloned oligonucleotides were checked by nucleotide sequencing.
- One important application is gene therapy, where it is necessary to deliver a gene or a synthetic oligonucleotide into the cell.
- The unmodified polynucleotides may be DNA, RNA or synthesized oligonucleotides.
- The latter is conjugated to primer oligonucleotides that are pre-annealed to a complementary circular oligonucleotide.
- The peptides can be linked to a large protein or an oligonucleotide, which may then be carried through the cell membrane.
- Intermolecular tetrameric complexes are usually only formed by short oligonucleotides that contain single tracts of contiguous guanines.
- Creation and purification of the double-labeled oligonucleotide is synthetically demanding.
- The unzipping direction (order of nucleotides unzipped) was controlled by the selection of oligonucleotides.
- In vitro studies on novel DNA structures have mainly involved synthetic oligonucleotides based on naturally occurring sequences.
- These studies demonstrate that pre-existing cytosine methylation on oligonucleotides…