Definition of megaloblast in English:
megaloblast
noun ˈmɛɡələ(ʊ)blastˈmɛɡələˌblæst
Medicine A large, abnormally developed red blood cell typical of certain forms of anaemia, associated with a deficiency of folic acid or of vitamin B₁₂.
Example sentencesExamples
- Finding megaloblasts in the blood can help to diagnose anaemia but does not determine the cause.
- Enlarged red cells, called megaloblasts, are caused by vitamin B12 deficiency and folate deficiency.
- Megaloblastic anemia is characterized by the presence of megaloblasts in the bone marrow.
- Enlarged red cells derived from megaloblasts are a consequence of a deficiency of vitamin B12 or folic acid.
- Ehrlich distinguished 3 types of granulated white blood cells, as well as normoblasts, megaloblasts, and leukemic cells.
Derivatives
adjective
Medicine She had megaloblastic changes in the bone marrow and chronic severe liver disease.
Example sentencesExamples
- Iron-deficiency anaemia and megaloblastic anaemia can occur during pregnancy.
- Three of these children revealed megaloblastic changes in bone marrow aspiration though their serum vitamin B12 and folate levels were normal.
- Folate and vitamin D deficiency may necessitate vitamin supplementations and, if uncorrected, leads to megaloblastic anemia.
- The classic affected patient who presents with neuropathy and megaloblastic anemia likely represents the minority of subjects with cobalamin deficiency.
Definition of megaloblast in US English:
megaloblast
nounˈmeɡələˌblastˈmɛɡələˌblæst
Medicine A large, abnormally developed red blood cell typical of certain forms of anemia, associated with a deficiency of folic acid or of vitamin B₁₂.
Example sentencesExamples
- Finding megaloblasts in the blood can help to diagnose anaemia but does not determine the cause.
- Ehrlich distinguished 3 types of granulated white blood cells, as well as normoblasts, megaloblasts, and leukemic cells.
- Enlarged red cells derived from megaloblasts are a consequence of a deficiency of vitamin B12 or folic acid.
- Enlarged red cells, called megaloblasts, are caused by vitamin B12 deficiency and folate deficiency.
- Megaloblastic anemia is characterized by the presence of megaloblasts in the bone marrow.