Definition of physostigmine in English:

physostigmine

noun ˌfʌɪsəʊˈstɪɡmiːnˌfīsōˈstiɡmēn

mass nounChemistry

A compound which is the active ingredient of the Calabar bean and is used medicinally in eye drops on account of its anticholinesterase activity.
A tricyclic alkaloid; chemical formula: C₁₅H₂₁N₃O₂
Example sentencesExamples
- Compared with placebo, an infusion of physostigmine produced a 21% decrease in apnea-hypopnea index and a 23% increase in the minimum level of oxygen saturation.
- Some authorities have recommended against the use of physostigmine because of its frequent association with increased bronchial secretions and its rare association with asystole.
- Julian was interested in medicinal plants, particularly the Calabar bean whose active principle, physostigmine, was first isolated by the German chemists Jobst and Hesse in 1864.
- But since physostigmine could be isolated only from the Calabar bean, the drug was not readily available.
- The symptoms of anticholinergic overdose may be treated with physostigmine in a dosage of 1 to 2 mg given intramuscularly or intravenously at 20-minute intervals.

Origin

Mid 19th century: from the modern Latin genus name Physostigma (to which the Calabar bean belongs) + -ine⁴.

Definition of physostigmine in US English:

physostigmine

nounˌfīsōˈstiɡmēn

Chemistry

A compound that is the active ingredient of the Calabar bean and is used medicinally in eye drops because of its anticholinergic activity.
A tricyclic alkaloid; chemical formula: C₁₅H₂₁N₃O₂
Example sentencesExamples
- Some authorities have recommended against the use of physostigmine because of its frequent association with increased bronchial secretions and its rare association with asystole.
- Julian was interested in medicinal plants, particularly the Calabar bean whose active principle, physostigmine, was first isolated by the German chemists Jobst and Hesse in 1864.
- Compared with placebo, an infusion of physostigmine produced a 21% decrease in apnea-hypopnea index and a 23% increase in the minimum level of oxygen saturation.
- But since physostigmine could be isolated only from the Calabar bean, the drug was not readily available.
- The symptoms of anticholinergic overdose may be treated with physostigmine in a dosage of 1 to 2 mg given intramuscularly or intravenously at 20-minute intervals.

Origin

Mid 19th century: from the modern Latin genus name Physostigma (to which the Calabar bean belongs) + -ine.

单词	physostigmine
释义	Definition of physostigmine in English: physostigmine noun ˌfʌɪsəʊˈstɪɡmiːnˌfīsōˈstiɡmēn mass nounChemistry A compound which is the active ingredient of the Calabar bean and is used medicinally in eye drops on account of its anticholinesterase activity. A tricyclic alkaloid; chemical formula: C₁₅H₂₁N₃O₂ Example sentencesExamples Compared with placebo, an infusion of physostigmine produced a 21% decrease in apnea-hypopnea index and a 23% increase in the minimum level of oxygen saturation. Some authorities have recommended against the use of physostigmine because of its frequent association with increased bronchial secretions and its rare association with asystole. Julian was interested in medicinal plants, particularly the Calabar bean whose active principle, physostigmine, was first isolated by the German chemists Jobst and Hesse in 1864. But since physostigmine could be isolated only from the Calabar bean, the drug was not readily available. The symptoms of anticholinergic overdose may be treated with physostigmine in a dosage of 1 to 2 mg given intramuscularly or intravenously at 20-minute intervals. Origin Mid 19th century: from the modern Latin genus name Physostigma (to which the Calabar bean belongs) + -ine⁴. Definition of physostigmine in US English: physostigmine nounˌfīsōˈstiɡmēn Chemistry A compound that is the active ingredient of the Calabar bean and is used medicinally in eye drops because of its anticholinergic activity. A tricyclic alkaloid; chemical formula: C₁₅H₂₁N₃O₂ Example sentencesExamples Some authorities have recommended against the use of physostigmine because of its frequent association with increased bronchial secretions and its rare association with asystole. Julian was interested in medicinal plants, particularly the Calabar bean whose active principle, physostigmine, was first isolated by the German chemists Jobst and Hesse in 1864. Compared with placebo, an infusion of physostigmine produced a 21% decrease in apnea-hypopnea index and a 23% increase in the minimum level of oxygen saturation. But since physostigmine could be isolated only from the Calabar bean, the drug was not readily available. The symptoms of anticholinergic overdose may be treated with physostigmine in a dosage of 1 to 2 mg given intramuscularly or intravenously at 20-minute intervals. Origin Mid 19th century: from the modern Latin genus name Physostigma (to which the Calabar bean belongs) + -ine.
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