Any of a class of animal transmembrane proteins involved in the adhesion of cells to each other and to their substrate.
Example sentencesExamples
- The expression of integrins on the cell surface facilitates adhesion.
- Understanding the nature of the interaction between the integrin and cell adhesion molecules can aid in the design of potent therapeutics.
- Transmembrane proteins, such as integrins, anchor cells to the substrate.
- The elucidation of the fly genome makes it relatively straightforward to generate and study mutations in proteins previously associated with integrins from other systems.
- This process is coordinately regulated by the spatial and temporal expression of integrins across the cell surface.