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单词 monosomy
释义

Definition of monosomy in English:

monosomy

noun ˌmɒnə(ʊ)ˈsəʊmiˈmɑnəˌsoʊmi
mass nounBiology
  • The condition of having a diploid chromosome complement in which one chromosome lacks its homologous partner.

    Example sentencesExamples
    • We conclude that chromosomes with damaged centromeres fail to correctly attach to the spindle, thus producing MN and monosomy.
    • Isochromosome 17 in this tumor may be functionally equivalent to monosomy 17, as the short arm is lost.
    • One plant lacked all six chromosome 12 markers, which indicates possible monosomy, and the other lacked just a terminal marker from the end of chromosome 10.
    • The predominant anomalies in reproductive specimens include trisomy of the autosomes and monosomy of the X chromosome.
    • Both monosomy and trisomy of specific chromosomes are associated with developmental defects and cancer risk.

Derivatives

  • monosomic

  • adjective
    Biology
    • Each type of monosomic and monotelodisomic aneuploid exhibits a characteristic chromosome-specific phenotypic syndrome.
      Example sentencesExamples
      • The selected nuclei are monosomic for the chromosome that carries the darA mutation; or they are disomic, and mitotic recombination has rendered the mutation homozygous.
      • A nucleus with one green signal was considered monosomic for chromosome 8 and one with three hybridization signals as trisomic.
      • Depending upon which sperm fertilizes the egg, the resulting plant will be trisomic or monosomic for the translocated A region.
      • A new marker on LG D04, the homeolog of chromosome 10, showed the G. barbadense allele in a cytogenetic stock monosomic for chromosome 20.
 
 

Definition of monosomy in US English:

monosomy

nounˈmänəˌsōmēˈmɑnəˌsoʊmi
Biology
  • The condition of having a diploid chromosome complement in which one (usually the X) chromosome lacks its homologous partner.

    Example sentencesExamples
    • One plant lacked all six chromosome 12 markers, which indicates possible monosomy, and the other lacked just a terminal marker from the end of chromosome 10.
    • We conclude that chromosomes with damaged centromeres fail to correctly attach to the spindle, thus producing MN and monosomy.
    • The predominant anomalies in reproductive specimens include trisomy of the autosomes and monosomy of the X chromosome.
    • Isochromosome 17 in this tumor may be functionally equivalent to monosomy 17, as the short arm is lost.
    • Both monosomy and trisomy of specific chromosomes are associated with developmental defects and cancer risk.
 
 
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更新时间:2025/1/11 16:22:34