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单词 proguanil
释义

Definition of proguanil in English:

proguanil

noun prəʊˈɡwɑːnɪl
mass nounMedicine
  • A bitter-tasting synthetic compound derived from biguanide, used in the prevention and treatment of malaria.

    Example sentencesExamples
    • They had taken chloroquine weekly and proguanil daily for chemoprophylaxis against malaria.
    • Another study comparing four prophylactic regimens in civilian travelers found that overall tolerability was the same among mefloquine, doxycycline, chloroquine plus proguanil, and atovaquone plus proguanil.
    • Mefloquine is not standard treatment internationally, although alternative drugs such as atovaquone with proguanil or artemether with lumefantrine may help to manage uncomplicated malaria in an ambulatory setting.
    • A separate combination, atovaquone plus proguanil, is active against malaria around the world.
    • Chloroquine with or without proguanil is used in some areas and Fansidar in others.

Origin

1940s: from pro(pyl) + (bi)guan(ide) (a crystalline base) + -il.

 
 
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更新时间:2024/12/23 16:01:04