释义 |
Definition of proguanil in English: proguanilnoun prəʊˈɡwɑːnɪl mass nounMedicine A bitter-tasting synthetic compound derived from biguanide, used in the prevention and treatment of malaria. Example sentencesExamples - They had taken chloroquine weekly and proguanil daily for chemoprophylaxis against malaria.
- Another study comparing four prophylactic regimens in civilian travelers found that overall tolerability was the same among mefloquine, doxycycline, chloroquine plus proguanil, and atovaquone plus proguanil.
- Mefloquine is not standard treatment internationally, although alternative drugs such as atovaquone with proguanil or artemether with lumefantrine may help to manage uncomplicated malaria in an ambulatory setting.
- A separate combination, atovaquone plus proguanil, is active against malaria around the world.
- Chloroquine with or without proguanil is used in some areas and Fansidar in others.
Origin 1940s: from pro(pyl) + (bi)guan(ide) (a crystalline base) + -il. |