A city in southern Florida, at the southern tip of the Florida Keys; population 22,364 (est. 2008). It is the southernmost city in the continental US.
Definition of Key West in US English:
Key West
proper nounkiːˈwest
A city in southern Florida, on Key West Island, at the southern tip of the Florida Keys; population 22,364 (est. 2008). It is the southernmost city in the continental US.