Definition of Klinefelter's syndrome in English:
Klinefelter's syndrome
nounˈklʌɪnˌfɛltəzˈklīnˌfeltərz ˌsindrōm
mass nounMedicine A syndrome affecting males in which the cells have an extra X chromosome (in addition to the normal XY), characterized by a tall thin physique, small infertile testes, and enlarged breasts.
Example sentencesExamples
- Men born with a genetic disorder called Klinefelter's syndrome often develop gynecomastia, as do males with adrenal tumors and liver disease.
- Risk factors for breast cancer in men suggest a hormonal imbalance, and up to 20 percent of male breast cancer cases have been associated with Klinefelter's syndrome.
- It is associated with breast and testicular abnormalities, infertility and Klinefelter's syndrome, a genetic abnormality in which men have one or more extra X chromosomes.
- For example, a screening check of Down's Syndrome might pick up the extra X chromosome that occurs in Chris's condition, Klinefelter's syndrome.
- In Klinefelter's syndrome, for instance, the presence of several X chromosomes and one Y chromosome sometimes results in sexual ‘ambiguity’.
Origin
1940s: named after Harry F. Klinefelter (born 1912), American physician.
Definition of Klinefelter's syndrome in US English:
Klinefelter's syndrome
nounˈklīnˌfeltərz ˌsindrōm
Medicine A syndrome affecting males in which the cells have an extra X chromosome (in addition to the normal XY), characterized by a tall thin physique, small infertile testes, and enlarged breasts.
Example sentencesExamples
- In Klinefelter's syndrome, for instance, the presence of several X chromosomes and one Y chromosome sometimes results in sexual ‘ambiguity’.
- Risk factors for breast cancer in men suggest a hormonal imbalance, and up to 20 percent of male breast cancer cases have been associated with Klinefelter's syndrome.
- Men born with a genetic disorder called Klinefelter's syndrome often develop gynecomastia, as do males with adrenal tumors and liver disease.
- It is associated with breast and testicular abnormalities, infertility and Klinefelter's syndrome, a genetic abnormality in which men have one or more extra X chromosomes.
- For example, a screening check of Down's Syndrome might pick up the extra X chromosome that occurs in Chris's condition, Klinefelter's syndrome.
Origin
1940s: named after Harry F. Klinefelter (born 1912), American physician.