| 释义 |
Definition of mutagen in English: mutagennoun ˈmjuːtədʒ(ə)nˈmjudədʒən An agent, such as radiation or a chemical substance, which causes genetic mutation. Example sentencesExamples - But we can provoke a quicker second hit by treating the animals with a chemical mutagen or a carcinogen.
- Among the mutagens that have been used to induce mutations, chemical mutagens administered in various ways have become especially popular.
- According to experimental data, some pesticides and organic solvents are considered potential chemical mutagens.
- The integrity and stability of the genetic material is continuously being threatened by endogenous and exogenous factors such as chemical mutagens and radiation.
- Detection of low frequency mutations following exposure to mutagens or during the early stages of cancer development is instrumental for risk assessment and molecular diagnosis.
- Exposure to ionizing radiation or environmental mutagens and carcinogens may lead to genomic instability.
- Firstly, risks to the descendants of trial participants because of the inadvertent modification of germ cells are not identical to those for chemical mutagens.
- The purpose of this study was to determine if cooked meat containing only moderate concentrations of the known food mutagens would be detectably mutagenic.
- One possible explanation for these exceptional findings might be contamination of the ethanol with a mutagen.
- Chemicals that cause changes in DNA sequence, or mutations, are called mutagens.
- These mutagens cause point mutations, because they change the genetic code at one point, so changing a protein's amino acid sequence.
- Unlike most chemical mutagens, which tend to cause point mutations, rays tend to produce larger aberrations such as chromosome deficiencies or rearrangements.
- Chemical mutagens and ionizing radiation have long been used as plant mutagens in forward genetic studies.
- We show here that these strains can be used to determine very easily the mutagenic specificity of various mutagens.
- Significantly, their findings were supported by both in vivo and in vitro experiments using reference mutagens.
- The so-called Ames test is based on the fact that most carcinogens are mutagens (substances that damage DNA).
- A host of carcinogens spew forth, along with poisons, mutagens, and mind-altering drugs.
- Cell-culture procedures, chemical mutagens, and radiation all have been applied in what people now refer to as traditional, or conventional, plant breeding for the better part of a century.
- For genetics and breeding, it is fundamentally important to know the germline mutation rate induced by a mutagen.
- Poisons, mutagens, and carcinogens might be created in harmful concentrations.
Derivatives noun ˌmjuːtəˈdʒɛnɪsɪsˌmjudəˈdʒɛnəsəs mass nounThe production of genetic mutations. in vitro mutagenesis could be used to determine which changes extend lifespan Example sentencesExamples - He was preeminent in the fields of mutagenesis and radiation biology.
- We carried out several rounds of mutagenesis for each chromosome arm.
- We and others have shown that studies of mutagenesis in cultured mammalian cells can help predict carcinogenesis.
adjective mjuːtəˈdʒɛnɪkˌmjudəˈdʒɛnɪk Lead is clearly not a powerful mutagen, nor is it consistently mutagenic among various test systems. Example sentencesExamples - This cell line detects a wide variety of mutagenic lesions, including point mutations, deletions and various types of chromosomal aberrations.
- Substances which allow the Salmonella to grow are considered mutagenic.
- This suggests a mutagenic source different from germ cell replication.
- Many carcinogens and mutagens have to be metabolized before their mutagenic activity can be detected.
noun mjuːtədʒ(ə)ˈnɪsɪti
Origin 1940s: from mutation + -gen. Definition of mutagen in US English: mutagennounˈmyo͞odəjənˈmjudədʒən An agent, such as radiation or a chemical substance, which causes genetic mutation. Example sentencesExamples - One possible explanation for these exceptional findings might be contamination of the ethanol with a mutagen.
- Poisons, mutagens, and carcinogens might be created in harmful concentrations.
- We show here that these strains can be used to determine very easily the mutagenic specificity of various mutagens.
- Cell-culture procedures, chemical mutagens, and radiation all have been applied in what people now refer to as traditional, or conventional, plant breeding for the better part of a century.
- The purpose of this study was to determine if cooked meat containing only moderate concentrations of the known food mutagens would be detectably mutagenic.
- The so-called Ames test is based on the fact that most carcinogens are mutagens (substances that damage DNA).
- The integrity and stability of the genetic material is continuously being threatened by endogenous and exogenous factors such as chemical mutagens and radiation.
- Among the mutagens that have been used to induce mutations, chemical mutagens administered in various ways have become especially popular.
- Exposure to ionizing radiation or environmental mutagens and carcinogens may lead to genomic instability.
- These mutagens cause point mutations, because they change the genetic code at one point, so changing a protein's amino acid sequence.
- Chemicals that cause changes in DNA sequence, or mutations, are called mutagens.
- Detection of low frequency mutations following exposure to mutagens or during the early stages of cancer development is instrumental for risk assessment and molecular diagnosis.
- But we can provoke a quicker second hit by treating the animals with a chemical mutagen or a carcinogen.
- Firstly, risks to the descendants of trial participants because of the inadvertent modification of germ cells are not identical to those for chemical mutagens.
- A host of carcinogens spew forth, along with poisons, mutagens, and mind-altering drugs.
- Significantly, their findings were supported by both in vivo and in vitro experiments using reference mutagens.
- For genetics and breeding, it is fundamentally important to know the germline mutation rate induced by a mutagen.
- Chemical mutagens and ionizing radiation have long been used as plant mutagens in forward genetic studies.
- Unlike most chemical mutagens, which tend to cause point mutations, rays tend to produce larger aberrations such as chromosome deficiencies or rearrangements.
- According to experimental data, some pesticides and organic solvents are considered potential chemical mutagens.
Origin 1940s: from mutation + -gen. |