Definition of paracrine in English:
paracrine
adjective ˈparəkrʌɪnˈperəkrən
Physiology Relating to or denoting a hormone which has effect only in the vicinity of the gland secreting it.
Example sentencesExamples
- Numerous studies have examined the role of paracrine interactions within islets and the importance of gap junctions to islet stimulus-secretion coupling.
- The excitability of DRG neurons may reflect a previously unsuspected chemosensory or paracrine role played by sensory ganglia.
- Here, we systematically derive discrete models of cell-to-cell communication from a mechanistic description of autocrine and paracrine signaling in epithelial layers.
- It was suggested that beta-cell cAMP levels in islets are greater than those in dispersed cells due to the paracrine secretion of glucagon by islet a-cells, which was expected to increase release rate and lead to faster bursting.
- To assess the possible involvement of a paracrine mechanism, normal human keratinocytes were exposed to SSR and culture medium was collected 24 h later.
Origin
1970s: from para-1 'beside' + krinein 'to separate'.