Definition of prostacyclin in English:
prostacyclin
noun ˌprɒstəˈsʌɪklɪnˌprästəˈsīklin
mass nounBiochemistry A compound of the prostaglandin type produced in arterial walls, which functions as an anticoagulant and vasodilator.
Example sentencesExamples
- The endothelium produces several regulatory mediators, including nitric oxide and prostacyclin, which are vasodilators, and endothelin, which is a vasoconstrictor.
- Aspirin also reduces endothelial cell production of prostacyclin, an inhibitor of platelet aggregation and a vasodilator.
- Prostaglandins, especially prostacyclin, are secreted in all veins and have a distinct antiplatelet-aggregating property.
- Other common therapies including anticoagulant treatment and prostacyclin have been used.
- Thromboxane is regulated by prostacyclin released from injured epithelial cells through negative feedback.
Origin
1970s: from prostaglandin + cyclic + -in1.