Definition of pseudouridine in English:
pseudouridine
nounˌsjuːdəʊˈjʊərɪdiːnˌso͞odōˈyo͝orədēn
mass nounBiochemistry A nucleoside present in transfer RNA and differing from uridine in having the sugar residue attached at a carbon atom instead of nitrogen.
Example sentencesExamples
- PSEUDOURIDINE has occurred in all hitherto analysed biological systems as a component of soluble ribonucleic acid.
- A marker of protein breakdown, urinary pseudouridine, was higher in the patients than in the healthy subjects: 25.1 versus 14.0 mmol per mmol creatinine.
- We assessed the clearance of endogenous pseudouridine in humans to evaluate the potential use of this modified nucleoside as a marker of glomerular filtration rate.
- Excretion of pseudouridine (5-ribosyluracil, PSU), a modified nucleoside indicator of RNA and hence of cellular protein breakdown, is increased in disease states associated with chronic systemic inflammation.