Definition of penetrance in English:

penetrance

noun ˈpɛnɪtr(ə)nsˈpenətrəns

mass nounGenetics

The extent to which a particular gene or set of genes is expressed in the phenotypes of individuals carrying it, measured by the proportion of carriers showing the characteristic phenotype.
Example sentencesExamples
- With the exception of the relatively rare high penetrance, single gene disorders, genetic tests differ little from most other medical tests, providing evidence of statistical risk only.
- Because of reduced penetrance, individuals of different genotypes can have the same phenotype.
- The penetrance of these phenotypes was background dependent.
- High penetrance susceptibility genes probably account for no more than 5-10% of cases.
- However, other low penetrance susceptibility genes may exist which may alter individual predisposition to breast cancer.

Origin

1930s: from German Penetranz.

Definition of penetrance in US English:

penetrance

nounˈpenətrəns

Genetics

The extent to which a particular gene or set of genes is expressed in the phenotypes of individuals carrying it, measured by the proportion of carriers showing the characteristic phenotype.
Example sentencesExamples
- High penetrance susceptibility genes probably account for no more than 5-10% of cases.
- Because of reduced penetrance, individuals of different genotypes can have the same phenotype.
- With the exception of the relatively rare high penetrance, single gene disorders, genetic tests differ little from most other medical tests, providing evidence of statistical risk only.
- The penetrance of these phenotypes was background dependent.
- However, other low penetrance susceptibility genes may exist which may alter individual predisposition to breast cancer.

Origin

1930s: from German Penetranz.

单词	penetrance
释义	Definition of penetrance in English: penetrance noun ˈpɛnɪtr(ə)nsˈpenətrəns mass nounGenetics The extent to which a particular gene or set of genes is expressed in the phenotypes of individuals carrying it, measured by the proportion of carriers showing the characteristic phenotype. Example sentencesExamples With the exception of the relatively rare high penetrance, single gene disorders, genetic tests differ little from most other medical tests, providing evidence of statistical risk only. Because of reduced penetrance, individuals of different genotypes can have the same phenotype. The penetrance of these phenotypes was background dependent. High penetrance susceptibility genes probably account for no more than 5-10% of cases. However, other low penetrance susceptibility genes may exist which may alter individual predisposition to breast cancer. Origin 1930s: from German Penetranz. Definition of penetrance in US English: penetrance nounˈpenətrəns Genetics The extent to which a particular gene or set of genes is expressed in the phenotypes of individuals carrying it, measured by the proportion of carriers showing the characteristic phenotype. Example sentencesExamples High penetrance susceptibility genes probably account for no more than 5-10% of cases. Because of reduced penetrance, individuals of different genotypes can have the same phenotype. With the exception of the relatively rare high penetrance, single gene disorders, genetic tests differ little from most other medical tests, providing evidence of statistical risk only. The penetrance of these phenotypes was background dependent. However, other low penetrance susceptibility genes may exist which may alter individual predisposition to breast cancer. Origin 1930s: from German Penetranz.
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