Definition of macrolide in US English:
macrolide
noun ˈmakrəˌlīdˈmakrəˌlīd
Any of a class of antibiotics containing a lactone ring, of which the first and best known is erythromycin.
Example sentencesExamples
- Methylation does not affect the function of the adenine residue other than to help the organism become less susceptible to the macrolide class of antibiotics.
- As with other currently available fluoroquinolone and macrolide antibiotics, QTc interval prolongation has been linked to the use of telithromycin.
- Trials investigating the role of macrolide antibiotic therapy in patients with acute coronary syndromes are inconclusive.
- Oral antibiotic therapy with macrolides and cephalosporines for presumed pneumonia was started, with a favorable response after 5 days of therapy.
- If antibiotics are required, one that is active against gram-positive organisms such as penicillinase-resistant penicillins, cephalosporins, macrolides, or fluoroquinolones should be chosen.
Origin
1950s: from macro- + l(actone) + -ide.