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单词 titrate
释义

Definition of titrate in English:

titrate

verbtɪˈtreɪttʌɪˈtreɪtˈtaɪˌtreɪt
[with object]Chemistry
  • 1Ascertain the amount of a constituent in (a solution) by measuring the volume of a known concentration of reagent required to complete a reaction with it, typically using an indicator.

    the sample is titrated at a pH near 10 with EDTA solution
    titrate 25 cm³ of this solution against 0.10 M hydrochloric acid
    Example sentencesExamples
    • Aliquots of the peptide solution were titrated to the micelle solution to reach a peptide-to-micelle molar ratio of 1: 220.
    • A specific weight of the compound is titrated with a known concentration of acid or base until the equivalence point has been reached.
    • To determine the exact concentration, titrating the hydrochloric acid against a solution of base, for example sodium hydroxide, would be appropriate.
    • The calorimetric profiles were nonlinear with increasing slope for the case when DNA was titrated into lipid solution, and the endpoint was rate dependent.
    • This solution was titrated with the HSA fragment by adding small amounts of an ~ 0.3 mM protein solution in the aqueous buffer and recording the spectrum after incubation for a few minutes after each addition.
    1. 1.1Medicine Continuously measure and adjust the balance of (a physiological function or drug dosage)
      each patient received intravenous diazepam and pethidine, the doses being titrated according to the response
      Example sentencesExamples
      • In general, high doses of steroids are required, but the dosage is titrated against the response and kept to the lowest effective dose, given for as short a time as possible.
      • Dosages were titrated for both medications by a treating psychiatrist at weekly follow-up visits.
      • Generally, a longer-acting benzodiazepine such as chlordiazepoxide is used, and the initial dosage is titrated downward according to blood pressure elevation, pulse rate, temperature and psychotic symptoms.
      • The initial dose of ritodrine was 50 mg per minute, and then the dosage was titrated to contractions.
      • Symptoms include abdominal discomfort, metallic taste, nausea, and diarrhea; these effects are generally transient and can be minimized by taking the drug with meals and titrating the dose slowly.

Derivatives

  • titratable

  • adjective
    • The only extra hydrogen bond that is formed involving titratable residues is between OG1 and OE2.
      Example sentencesExamples
      • The relationship between titratable acidity and malic acid was less obvious.
      • The sign and magnitude of the pK a shift of a particular titratable group is determined by the free energy to transfer it into the low-dielectric protein cavity, and by its interactions with polar residues in the protein.
      • We surmise that protonation of titratable residues of the HA1 domain at low pH enhances the electrostatic repulsion between the monomers of the globular domain and thus lowers the stability of their association.
      • Thus, it is reasonable to assume that the protonation of the titratable residues on the HA1 surface is mainly influenced by other residues of HA1 and that effects from HA2 domain may be negligible.
  • titration

  • nountɪˈtreɪʃ(ə)ntʌɪˈtreɪʃ(ə)n
    • The titration was done in Philadelphia and Courtois was told to dilute the material sixty-fold in order to reach the desired dose.
      Example sentencesExamples
      • The reasons for these 32 repeated titrations were excessive leakage in 20 cases and a registration period under 6 hours or a sleep time under 5 hours (subjectively appreciated by the patient) in the remaining 12 cases.
      • The titrations were performed with various concentrations of TFE, SDS, and DPC.
      • Increases of 40% to 70% in fluorescence intensity are in the range of hyperfluorescence observed during unfolding titrations of proteins.
      • So if Plotkin is correct when he says that the titration was done in Philadelphia, this would mean that the vaccine fed in Africa was of unknown titre.

Origin

Late 19th century: from French titrer (from titre in the sense 'fineness of alloyed gold or silver') + -ate3.

 
 

Definition of titrate in US English:

titrate

verbˈtaɪˌtreɪtˈtīˌtrāt
[with object]Chemistry
  • 1Ascertain the amount of a constituent in (a solution) by measuring the volume of a known concentration of reagent required to complete a reaction with it, typically using an indicator.

    the sample is titrated at a pH near 10 with EDTA solution
    titrate 25 cm³ of this solution against 0.10 M hydrochloric acid
    Example sentencesExamples
    • A specific weight of the compound is titrated with a known concentration of acid or base until the equivalence point has been reached.
    • Aliquots of the peptide solution were titrated to the micelle solution to reach a peptide-to-micelle molar ratio of 1: 220.
    • This solution was titrated with the HSA fragment by adding small amounts of an ~ 0.3 mM protein solution in the aqueous buffer and recording the spectrum after incubation for a few minutes after each addition.
    • The calorimetric profiles were nonlinear with increasing slope for the case when DNA was titrated into lipid solution, and the endpoint was rate dependent.
    • To determine the exact concentration, titrating the hydrochloric acid against a solution of base, for example sodium hydroxide, would be appropriate.
    1. 1.1Medicine Continuously measure and adjust the balance of (a physiological function or drug dosage)
      each patient received intravenous diazepam and pethidine, the doses being titrated according to the response
      Example sentencesExamples
      • Symptoms include abdominal discomfort, metallic taste, nausea, and diarrhea; these effects are generally transient and can be minimized by taking the drug with meals and titrating the dose slowly.
      • In general, high doses of steroids are required, but the dosage is titrated against the response and kept to the lowest effective dose, given for as short a time as possible.
      • Dosages were titrated for both medications by a treating psychiatrist at weekly follow-up visits.
      • The initial dose of ritodrine was 50 mg per minute, and then the dosage was titrated to contractions.
      • Generally, a longer-acting benzodiazepine such as chlordiazepoxide is used, and the initial dosage is titrated downward according to blood pressure elevation, pulse rate, temperature and psychotic symptoms.

Origin

Late 19th century: from French titrer (from titre in the sense ‘fineness of alloyed gold or silver’) + -ate.

 
 
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更新时间:2025/1/27 21:44:23