Definition of syngeneic in English:
syngeneic
adjective ˌsɪndʒɪˈneɪɪkˌsɪndʒɪˈniːɪkˌsinjəˈnēik
Biology Medicine (of organisms or cells) genetically similar or identical and hence immunologically compatible, especially so closely related that transplantation does not provoke an immune response.
the rejection by an animal of a syngeneic tumour graft proves that the tumour cells carry their own specific antigens
Example sentencesExamples
- Furthermore, we reported that a pharmacologic inhibitor of IDO, 1-methyl tryptophan, induced maternal rejection of allogeneic but not syngeneic murine fetuses.
- These findings were also observed in syngeneic animals (although less frequently), particularly in the first 3 days after surgery.
- Three syngeneic animals and one animal with allograft had marked focal uptake of annexin V in a linear pattern corresponding to the left thoracotomy site.
- It was shown that spleen cells and infiltrating leukocytes isolated from well-functioning cardiac allografts in immunologically enhanced adult rats suppressed spontaneous blastogenesis of normal syngeneic cells in vitro.
- The cells produced potent stimulation of allogenic T cells and syngeneic T cells specific for purified protein derivative in the absence of exogenous peptides.
Origin
1960s: from syn- 'together' + Greek genea 'race, stock' + -ic.