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单词 syngeneic
释义

Definition of syngeneic in English:

syngeneic

adjective ˌsɪndʒɪˈneɪɪkˌsɪndʒɪˈniːɪkˌsinjəˈnēik
Biology Medicine
  • (of organisms or cells) genetically similar or identical and hence immunologically compatible, especially so closely related that transplantation does not provoke an immune response.

    the rejection by an animal of a syngeneic tumour graft proves that the tumour cells carry their own specific antigens
    Example sentencesExamples
    • Furthermore, we reported that a pharmacologic inhibitor of IDO, 1-methyl tryptophan, induced maternal rejection of allogeneic but not syngeneic murine fetuses.
    • These findings were also observed in syngeneic animals (although less frequently), particularly in the first 3 days after surgery.
    • Three syngeneic animals and one animal with allograft had marked focal uptake of annexin V in a linear pattern corresponding to the left thoracotomy site.
    • It was shown that spleen cells and infiltrating leukocytes isolated from well-functioning cardiac allografts in immunologically enhanced adult rats suppressed spontaneous blastogenesis of normal syngeneic cells in vitro.
    • The cells produced potent stimulation of allogenic T cells and syngeneic T cells specific for purified protein derivative in the absence of exogenous peptides.

Origin

1960s: from syn- 'together' + Greek genea 'race, stock' + -ic.

 
 

Definition of syngeneic in US English:

syngeneic

adjectiveˌsinjəˈnēik
Medicine Biology
  • (of organisms or cells) genetically similar or identical and hence immunologically compatible, especially so closely related that transplantation does not provoke an immune response.

    the rejection by an animal of a syngeneic tumor graft proves that the tumor cells carry their own specific antigens
    Example sentencesExamples
    • Three syngeneic animals and one animal with allograft had marked focal uptake of annexin V in a linear pattern corresponding to the left thoracotomy site.
    • The cells produced potent stimulation of allogenic T cells and syngeneic T cells specific for purified protein derivative in the absence of exogenous peptides.
    • Furthermore, we reported that a pharmacologic inhibitor of IDO, 1-methyl tryptophan, induced maternal rejection of allogeneic but not syngeneic murine fetuses.
    • It was shown that spleen cells and infiltrating leukocytes isolated from well-functioning cardiac allografts in immunologically enhanced adult rats suppressed spontaneous blastogenesis of normal syngeneic cells in vitro.
    • These findings were also observed in syngeneic animals (although less frequently), particularly in the first 3 days after surgery.

Origin

1960s: from syn- ‘together’ + Greek genea ‘race, stock’ + -ic.

 
 
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更新时间:2025/1/27 21:58:23