Definition of exonuclease in English:
exonuclease
nounˌɛksəʊˈnjuːklɪeɪzˌeksōˈn(y)o͞oklēās
Biochemistry An enzyme which removes successive nucleotides from the end of a polynucleotide molecule.
Example sentencesExamples
- A given exonuclease hydrolyzes DNA at a fixed rate, but there exist a distribution of conformations and a distribution of hydrolysis rates.
- Orn was shown by in vitro analysis to be an exonuclease specific for RNA molecules shorter than five nucleotides in length.
- The binding mechanism of psoralens to a double-strand DNA has been well investigated by chemical and enzymatic methods using restriction enzymes and exonuclease.
- The rapid rise of the first fluorescence maximum puts a strict upper bound on the timescale of magnesium binding to the exonuclease.
- Phage gene 46 encodes one subunit of a putative exonuclease that is thought to be directly involved in recombination and recombinational repair.