| 释义 |
Definition of cyclic GMP in US English: cyclic GMP(also cGMP) noun A cyclic version of the nucleotide guanosine monophosphate. In cellular metabolism, it is a secondary messenger affecting cell growth and division. Example sentencesExamples - The carbon monoxide activates the enzyme guanylyl cyclase, as does nitric oxide, regulating the intracellular levels of the second messenger cyclic GMP, which in turn regulates cellular activity.
- Guanylyl-cyclase activators are nitric oxide donors that increase cyclic GMP.
- A second messenger of internal cellular communication - cyclic GMP, produced in response to nitric oxide - is a key regulator of vascular smooth muscle cell contractility, growth, and differentiation.
- The resulting vasodilation has been potentially attributed to inhibition of cyclic nucleotide phosphodiesterases, with resulting increases in intracellular levels of cyclic AMP and cyclic GMP accompanied by decreases in Ca.
- We thought we could more strongly apply the brake on hypertrophy in the heart if we used sildenafil to prevent the breakdown of cyclic GMP.
Definition of cyclic GMP in US English: cyclic GMP(also cGMP) noun A cyclic version of the nucleotide guanosine monophosphate. In cellular metabolism, it is a secondary messenger affecting cell growth and division. Example sentencesExamples - Guanylyl-cyclase activators are nitric oxide donors that increase cyclic GMP.
- We thought we could more strongly apply the brake on hypertrophy in the heart if we used sildenafil to prevent the breakdown of cyclic GMP.
- A second messenger of internal cellular communication - cyclic GMP, produced in response to nitric oxide - is a key regulator of vascular smooth muscle cell contractility, growth, and differentiation.
- The carbon monoxide activates the enzyme guanylyl cyclase, as does nitric oxide, regulating the intracellular levels of the second messenger cyclic GMP, which in turn regulates cellular activity.
- The resulting vasodilation has been potentially attributed to inhibition of cyclic nucleotide phosphodiesterases, with resulting increases in intracellular levels of cyclic AMP and cyclic GMP accompanied by decreases in Ca.
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