Definition of cytochalasin in English:
cytochalasin
noun ˌsʌɪtəʊkəˈleɪsɪnˌsīdəkəˈlās(ə)n
mass nounBiochemistry Any of a group of polycyclic compounds produced by fungi, used experimentally in research for their property of interfering with cell processes.
Example sentencesExamples
- Cells at a reduced cholesterol concentration were treated with cytochalasin D.
- In experiments that test the effect of actin, cells were incubated for 30 min before experiments in medium containing 20 M cytochalasin D to disrupt actin filaments.
- At low concentrations, cytochalasin D is reported to inhibit actin polymerization.
- In stark contrast to cytochalasin, treatment with nocodazole did not produce a loss of any features; instead there was an increase in the density of filaments.
- We measured the effect of cytochalasin D mobilization of integrins on adhesion of a leukocyte cell line to both cultured endothelium and purified ligand substrates.
Origin
1960s: from cyto- 'cell' + Greek khalasis 'dislocation'.