Definition of cytotoxic in English:
cytotoxic
adjective sʌɪtə(ʊ)ˈtɒksɪkˌsaɪdəˈtɑksɪk
Toxic to living cells.
peripheral blood lymphocytes may be cytotoxic to these cells
Example sentencesExamples
- Drug treatment of cancer is often limited by unwanted tissue damage due to the lack of tumor selectivity of the cytotoxic agents administered.
- A hospital doctor has been charged with manslaughter over the death of a teenager who was wrongly given a spinal injection of a cytotoxic drug meant for intravenous use only.
- Earlier studies indicated that the fibrils themselves were the cytotoxic form of amyloid peptides.
- The ability to distinguish between the two cell types is not complete, and cytotoxic drugs cannot avoid causing some damage to normal cells.
- This reaction results in the production of oxygen radicals, which are cytotoxic to the tumor cells.
- Nurses usually prepared and administered intravenous drugs on the wards, but cytotoxic drugs were prepared centrally by the pharmacy department.
- Vitamin C is directly cytotoxic to certain cancer cell lines in vitro.
- A woman was exposed to a possible teratogen such as a live vaccine or cytotoxic drug when she was not protected by effective contraception.
- With cellular immune response, specific cytotoxic T cells are formed.
- Ganciclovir is a guanosine analog that becomes strongly cytotoxic when phosphorylated.
- The control experiment with ascorbate alone shows no noticeable cytotoxic action of sodium ascorbate.
- The catalytic antibody technology can localize the delivery of a cytotoxic drug to a specific cell or cancer type.
- Physician office laboratories that handle cytotoxic drugs are required to have special procedures for handling these agents.
- A wide variety of agents has been discovered that stabilize such structures and exert cytotoxic effects on cells in culture.
- The free radicals and reactive species produced by these reactions are highly cytotoxic.
- She was subjected to an intensive combination of cytotoxic drugs and cranial radiotherapy.
- Leukocidin is a pore-forming protein that has cytotoxic effects on host cells.
- Unsaturated aldehydes are often cytotoxic, and many of them are precursors of fluorescent products.
- Pores in membranes can be induced by cytotoxic peptide antibiotics and by peptide fragments of viral glycoproteins.
- The fibrils formed by the hexapeptide were also cytotoxic toward the pancreatic cell line.
Derivatives
noun
It has been suggested that sequestration of bile acids by intracellular bile acid binding proteins may also protect cells from bile acid cytotoxicity.
Example sentencesExamples
- In vitro, these peptides inhibited cytotoxicity and differentiation of cytotoxic T cells.
- Thus it appears that PHP-mediated cytotoxicity proceeds through both membrane and mitochondrial photosensitization.
- The initial photooxidative injury triggers a number of responses, including direct cytotoxicity within the tumor microenvironment.
- We attributed the reduced cytotoxicity at higher repetition rates to the contribution of the oxygen-independent mechanism.
Definition of cytotoxic in US English:
cytotoxic
adjectiveˌsīdəˈtäksikˌsaɪdəˈtɑksɪk
Toxic to living cells.
peripheral blood lymphocytes may be cytotoxic to these cells
Example sentencesExamples
- With cellular immune response, specific cytotoxic T cells are formed.
- Pores in membranes can be induced by cytotoxic peptide antibiotics and by peptide fragments of viral glycoproteins.
- Physician office laboratories that handle cytotoxic drugs are required to have special procedures for handling these agents.
- Earlier studies indicated that the fibrils themselves were the cytotoxic form of amyloid peptides.
- Ganciclovir is a guanosine analog that becomes strongly cytotoxic when phosphorylated.
- The fibrils formed by the hexapeptide were also cytotoxic toward the pancreatic cell line.
- Nurses usually prepared and administered intravenous drugs on the wards, but cytotoxic drugs were prepared centrally by the pharmacy department.
- The free radicals and reactive species produced by these reactions are highly cytotoxic.
- The ability to distinguish between the two cell types is not complete, and cytotoxic drugs cannot avoid causing some damage to normal cells.
- Vitamin C is directly cytotoxic to certain cancer cell lines in vitro.
- A wide variety of agents has been discovered that stabilize such structures and exert cytotoxic effects on cells in culture.
- The control experiment with ascorbate alone shows no noticeable cytotoxic action of sodium ascorbate.
- She was subjected to an intensive combination of cytotoxic drugs and cranial radiotherapy.
- A woman was exposed to a possible teratogen such as a live vaccine or cytotoxic drug when she was not protected by effective contraception.
- The catalytic antibody technology can localize the delivery of a cytotoxic drug to a specific cell or cancer type.
- Unsaturated aldehydes are often cytotoxic, and many of them are precursors of fluorescent products.
- This reaction results in the production of oxygen radicals, which are cytotoxic to the tumor cells.
- Leukocidin is a pore-forming protein that has cytotoxic effects on host cells.
- A hospital doctor has been charged with manslaughter over the death of a teenager who was wrongly given a spinal injection of a cytotoxic drug meant for intravenous use only.
- Drug treatment of cancer is often limited by unwanted tissue damage due to the lack of tumor selectivity of the cytotoxic agents administered.