synuclein
/sɪˈnjuːklɪɪn/Biochemistry
noun
Any of a group of three small proteins which are found in neurons, especially near synapses, and are of uncertain function; especially (in full alpha-synuclein) a protein of this family which is the major component of an abnormal structure (the Lewy body) found in neurons in Parkinson's disease and certain other neurodegenerative disorders.
- Mutations in the gene coding for alpha-synuclein are responsible for inherited forms of Parkinson's disease..
Origin
1980s. From sy- + nucle- + -in; the proteins were isolated in a study of the synapses and electromotor nucleus of the electric organ in the electric ray Torpedo.
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